At onlinemeds, we support hundreds of patients each month on their weight loss journeys using clinically approved treatments. Two of the most in-demand injectable medications right now are Mounjaro and Wegovy—and it’s no surprise that many people are wondering which one is best for them.

To help you make an informed choice, we’ve put together this Mounjaro vs Wegovy Q&A, answering the most common questions we receive from patients.

Q: What are Mounjaro and Wegovy, and how do they work?

A: Both Mounjaro (tirzepatide) and Wegovy (semaglutide) are injectable medications that help with weight loss by regulating your appetite and how your body responds to food.

Wegovy is a GLP-1 receptor agonist, mimicking a hormone that signals fullness to your brain.

Mounjaro is a dual-action drug—it targets both GLP-1 and GIP receptors, offering an additional layer of appetite regulation and metabolic control.

Both are designed to help you eat less, feel fuller sooner, and support gradual, sustainable weight loss when used alongside diet and lifestyle changes.

Q: Which is more effective—Mounjaro or Wegovy?

A: Clinical trials suggest that Mounjaro may lead to greater weight loss on average than Wegovy. Some patients have achieved over 20% body weight reduction with Mounjaro compared to 15–17% with Wegovy, depending on dosage and duration of treatment.

That said, effectiveness can vary based on your personal health, lifestyle, and how your body responds to treatment. At onlinemeds, we assess each patient individually to determine the most suitable option.

Q: How often do I need to take each medication?

A: Both medications are administered via once-weekly injections, typically into the stomach, thigh, or upper arm.

Wegovy comes in pre-filled pens with fixed doses.

Mounjaro also uses a pre-filled pen, but its dosage range and escalation schedule differ slightly.

We provide easy-to-follow guidance with every prescription to ensure you’re confident in administering your medication correctly.

Q: Are there any side effects I should know about?

A: Yes, both medications can cause side effects—most commonly:

• –> Nausea

• –> Diarrhoea or constipation

• –> Fatigue

• –> Reduced appetite

• –> Headache

These side effects are usually mild and improve over time. In rare cases, more serious effects like pancreatitis can occur. That’s why we recommend ongoing support and monitoring, which we offer as part of our onlinemeds care service.

Q: Can anyone use Mounjaro or Wegovy?

A: These medications are intended for adults with a BMI of 30 or higher (obese), or a BMI of 27 or higher with weight-related health conditions (such as high blood pressure, type 2 diabetes, or sleep apnoea)

They are not suitable for those who are pregnant, breastfeeding, or have certain medical conditions. Our pharmacy team conducts a full clinical assessment before prescribing.

Q: Are these treatments available on the NHS?

A: Wegovy is currently available on the NHS in certain situations, such as through weight management services. However, access is limited and often involves long waiting times.

Mounjaro is available privately in the UK, including through onlinemeds, but it’s not yet widely accessible on the NHS for weight loss purposes (though it may be used for type 2 diabetes in some cases).

If you’re looking for a quicker and more personalised service, private prescription via onlinemeds is a convenient and safe option.

Q: How do I choose between Mounjaro vs Wegovy?

A: The right choice depends on your medical history, treatment goals, budget, and how you respond to the medication. Our clinicians consider all of these factors during your consultation. Some patients respond better to Wegovy, while others achieve more success with Mounjaro.

Whichever route you take, we provide ongoing support, clear instructions, and trusted advice every step of the way.

Q: How do I get started with onlinemeds?

A: It’s simple:

1. Complete an online consultation on our website.

2. Our pharmacy team will review your answers and ensure the treatment is appropriate.

3. If approved, your medication is dispatched discreetly and quickly with all the guidance you need.

4. We remain available to support your progress with regular check-ins and advice.

Contact us today if you have any questions.

Are You Ready to Take the Next Step?

Mounjaro vs Wegovy is a common comparison—and for good reason. Both are powerful, clinically proven treatments that can make a real difference when used responsibly. At onlinemeds, we take the time to help you understand your options and choose the one that’s right for your body and your goals.

Ready to take the next step? Complete your consultation today and begin your personalised, pharmacist-supported weight loss journey.