Doxycycline is an oral drug that helps to prevent malaria in travellers to malaria-endemic areas. The drug is a good option for places with chloroquine or multidrug-resistant P. falciparum. Doxycycline is swallowed once daily, beginning 1-2 days before travel, while in malaria-prone areas, and four weeks after leaving. It has a low chance of bacterial resistance, thus increasing effective treatment when taken as prescribed.
Doxycycline 100 mg daily is highly effective at killing the erythrocytic stages of the malaria parasite. It is tetracycline, with both antibacterial and antiprotozoal properties. Parasitic protozoans cause malaria, and the antiprotozoal properties are what help to prevent malaria. The drug helps prevent the production of vital proteins needed to make new malaria parasites in our bodies. Without the protein, the parasites die.
Do not take Doxycycline if you:
Each Doxycycline capsule contains 100mg Doxycycline as the active ingredient. Each capsule contains gelatin, magnesium stearate, shellac glaze, sodium lauryl sulfate, starch, E104, E127, E131, E171, E172, and propylene glycol.
Some common side effects:
The conditions below may indicate allergic reactions. Stop treatment and see your doctor if you notice:
1. When should I start taking doxycycline for malaria?
Start taking doxycycline 1-2 days before entering a malaria-prone area. Continue daily throughout the stay and for 4 weeks after leaving the area.
2. How effective is doxycycline for malaria prevention?
When taken correctly, doxycycline offers 90-100% protection against malaria. However, it should be used alongside other protective measures such as insect repellents and mosquito nets.
3. Can I take doxycycline with food?
Yes, you can take doxycycline with a meal to help minimise stomach upset. However, avoid taking it with dairy products or supplements containing iron, magnesium, or zinc, as they can reduce its effectiveness.
4. Is doxycycline suitable for children?
Doxycycline is not recommended for children under 12 years old due to the risk of tooth discoloration and effects on bone growth.
5. What if I miss a dose?
Take the missed dose as soon as you remember. If it’s almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not take two doses at the same time.