Foundayo Tablets

Price range: £115.00 through £162.00

Foundayo (orforglipron) is a once-daily prescription weight-loss tablet, licensed by the MHRA for adults with obesity, or who are overweight with a weight-related health condition.

Taken orally with no food or water restrictions, Foundayo works by reducing appetite to support meaningful weight loss alongside a reduced-calorie diet and increased physical activity.

Description

How Foundayo Works

Foundayo contains orforglipron, a GLP-1 receptor agonist. It works by mimicking GLP-1, a hormone your body produces naturally after eating, which acts on the areas of the brain that control appetite and fullness. This helps you feel fuller for longer, reduces hunger and cravings, and, as with other GLP-1 medicines, may also slow the movement of food through your stomach.

Unlike some other GLP-1 tablets, Foundayo isn’t a peptide — it’s a small-molecule medicine, which is part of why it can be taken at any time of day, with or without food.

Why Choose Foundayo Tablets?

  • A once-daily tablet — no injections, needles or sharps disposal
  • No food or water restrictions, unlike some other oral weight-loss tablets
  • A clear, gradual dosing schedule designed to help you build tolerance
  • Backed by Phase III clinical trial data over 72 weeks
  • MHRA-approved and only supplied following a clinical consultation

Who Can Use Foundayo?

Foundayo may be suitable for adults who:

  • Have a Body Mass Index (BMI) of 30 or above, or
  • Have a BMI of 27–30 with at least one weight-related health condition (such as high blood pressure or type 2 diabetes), and
  • Are committed to combining treatment with a reduced-calorie diet and increased physical activity

Foundayo may also be prescribed to adults with type 2 diabetes to help improve blood sugar control. Suitability is always confirmed by one of our prescribers during your online consultation, based on your medical history.

Important Safety Information

Foundayo is a prescription-only medicine (POM). It requires an online consultation with a UK-registered prescriber to assess its suitability before a prescription can be issued — it is not available to buy without one.

  • Not suitable for individuals under 18 years of age
  • Not suitable during pregnancy or while breastfeeding
  • Not suitable if you have a personal or family history of medullary thyroid cancer or Multiple Endocrine Neoplasia syndrome type 2 (MEN 2)
  • Not suitable if you have a known allergy to orforglipron or any of the tablet’s other ingredients

Key Takeaway

Foundayo offers a needle-free, once-daily option for medically supervised weight loss, with flexible dosing and no food or water restrictions. As with all prescription weight-loss treatments, it works best alongside sustainable lifestyle changes, isn’t suitable for everyone, and is only supplied after a clinical assessment.

Always take Foundayo exactly as directed by your prescriber. As a general guide:

  • Starting dose: 0.8mg, taken once daily
  • Your prescriber will increase your dose gradually — typically no more often than once a month — through 2.5mg, 5.5mg, 9mg and 14.5mg, up to a maintenance dose of 17.2mg
  • Take one tablet at any time of day, with or without food or water
  • Swallow the tablet whole with water, as directed on your prescription label
  • If you miss a dose, follow the guidance provided with your prescription or contact your prescriber

Storage Instructions

  • Store below 25°C — Foundayo does not need to be refrigerated
  • Keep tablets in their original packaging to protect them from light
  • Store out of sight and reach of children
  • Do not use after the expiry date shown on the pack

Active ingredient: orforglipron.

Foundayo tablets also contain other ingredients (excipients). A full list is provided in the Patient Information Leaflet (PIL) supplied with your medicine — please read this before starting treatment.

Like all medicines, Foundayo can cause side effects, although not everyone experiences them.

Common side effects

  • Nausea
  • Constipation
  • Diarrhoea
  • Vomiting
  • Indigestion (dyspepsia)
  • Abdominal pain

These tend to be mild to moderate and often ease as your body adjusts, particularly around dose increases.

Rare but serious side effects

As with other GLP-1 medicines, seek urgent medical advice if you experience severe, persistent abdominal pain (which may indicate pancreatitis), yellowing of the skin or eyes, or signs of a severe allergic reaction such as swelling of the face, lips or throat, or difficulty breathing.

  • May reduce the effectiveness of oral hormonal contraceptives — your prescriber may advise an additional or alternative method of contraception
  • May increase the risk of aspiration during procedures requiring general anaesthesia or deep sedation — tell your surgical or dental team you’re taking Foundayo before any such procedure
  • Use with caution if you have a history of pancreatitis, gallbladder problems, severe gastroparesis, diabetic eye disease (retinopathy), kidney problems, or severe heart failure
  • Tell your prescriber about all medicines you’re taking, including those you buy without a prescription
  • Foundayo is the brand name for orforglipron, a GLP-1 receptor agonist tablet that reduces appetite and increases feelings of fullness, helping you eat less as part of a wider weight-management plan that includes diet and exercise.
  • Adults with a BMI of 30 or above, or a BMI of 27–30 with a weight-related health condition, may be suitable, as may adults with type 2 diabetes. Final suitability is always confirmed during your consultation.
  • Many people notice reduced appetite within the first few weeks, but meaningful weight loss builds gradually as your dose is increased over several months. In clinical trials, results were measured over 72 weeks.
  • Foundayo, Wegovy and Mounjaro all belong to the GLP-1 family of medicines. Wegovy and Mounjaro are given by weekly injection, while Foundayo is taken as a once-daily tablet with no food or water restrictions, making it a needle-free alternative for people who prefer not to self-inject.
  • Yes. Foundayo is available following an online consultation with one of our UK-registered prescribers, who will review your medical history to confirm it's suitable for you — you don't need to see your GP first.
  • Foundayo is available in six strengths — 0.8mg, 2.5mg, 5.5mg, 9mg, 14.5mg and 17.2mg. Your prescriber will start you on the lowest dose and increase it gradually based on how you respond.