At onlinemeds, we know that choosing the right weight loss treatment can feel confusing, especially with the growing popularity of injectables. Two of the most widely discussed options are Wegovy and Mounjaro, both designed to support patients who are struggling to lose weight through diet and exercise alone. While they work in similar ways, there are some important differences to consider when deciding which treatment is right for you.

In this guide, we compare Wegovy vs Mounjaro, looking at how they work, their accessibility, expected results, costs and potential side effects. Understanding the pros and cons of each can help you make an informed decision, supported by medical advice.

How Wegovy and Mounjaro Work

Both Wegovy and Mounjaro are injectable medications designed to help regulate appetite and support weight loss. They work by mimicking hormones that affect hunger and satiety, helping you feel fuller for longer and making it easier to stick to a reduced-calorie diet.

Wegovy contains semaglutide, a GLP-1 receptor agonist, while Mounjaro contains tirzepatide, which acts on both GLP-1 and GIP receptors. This dual action makes Mounjaro slightly different in its mechanism and is one reason why some studies suggest it can achieve greater weight loss for certain patients.

Accessibility and Cost

When comparing Wegovy vs Mounjaro, availability and cost are significant factors. Wegovy has been available in the UK for longer, which means it is generally easier to access privately, and in some cases, it is also available through NHS weight management services for eligible patients.

Mounjaro is newer and has gained attention for its promising results, but recent supply issues and a notable increase in price have made access more limited. This means that for some patients, Wegovy may be a more accessible option both in terms of availability and affordability.

At onlinemeds, we can guide you through the options, discuss pricing transparently and help you decide which treatment best suits your circumstances.

wegovy vs mounjaro pros and cons

Expected Results and Success Rates

One of the key considerations when choosing between these treatments is what you can realistically expect in terms of results. Clinical studies show that both Wegovy and Mounjaro can support significant weight loss when used alongside healthy lifestyle changes.

Wegovy has demonstrated an average weight loss of around 15% of body weight in major clinical trials, while Mounjaro has shown slightly higher average reductions, in some cases exceeding 20% of body weight for certain patients. However, individual results can vary based on factors such as diet, activity levels and adherence to treatment.

It is important to remember that neither medication is a quick fix. For the best results, they should be combined with positive lifestyle changes, including balanced nutrition, regular exercise and ongoing professional support.

Side Effects and Tolerability

Like any treatment, Wegovy and Mounjaro can cause side effects, although many are mild and temporary. The most common side effects include nausea, diarrhoea, constipation, bloating and indigestion. These symptoms often improve as the body adjusts to the medication.

Some patients find Mounjaro slightly more tolerable because its dual mechanism can reduce gastrointestinal side effects, but experiences differ from person to person. Before starting treatment, it is important to have a full consultation to assess your medical history, review potential risks and ensure the chosen option is safe for you.

Pros and Cons of Wegovy

Pros:

  • –> Widely available privately and through NHS weight management services for some patients

  • –> Strong clinical evidence supporting effective weight loss

  • –> Once-weekly injection for convenience

  • –> Proven track record and more predictable accessibility

Cons:

  • –> Results may be slightly lower than Mounjaro for some patients

  • –> Can cause temporary digestive side effects

  • –> NHS access is restricted to specific eligibility criteria

Pros and Cons of Mounjaro

Pros:

  • –> Dual-action formula targets both GLP-1 and GIP receptors

  • –> Some studies suggest greater average weight loss than Wegovy

  • –> May offer improved appetite control for certain patients

  • –> Can be effective for people who have not responded to other treatments

Cons:

  • –> Less widely available than Wegovy in the UK

  • –> Recent price increases make it more costly privately

  • –> Potential supply limitations in some areas

  • –> Side effects are similar to Wegovy and can affect tolerability

Compare wegovy vs mounjaro

Making the Right Choice

When comparing Wegovy vs Mounjaro, there is no single best option for everyone. The right treatment depends on your health profile, weight loss goals, medical history and personal preferences. Some patients prefer Wegovy due to its accessibility and proven results, while others may choose Mounjaro for its potential to achieve greater weight loss.

At onlinemeds, we offer personalised consultations to assess your needs and recommend the most suitable treatment. Our clinicians review your medical history, explain the benefits and risks of each option and provide expert guidance so you can make an informed decision with confidence.

Start Your Weight Loss Journey with Onlinemeds

Weight loss is a personal journey, and choosing the right support is key to long-term success. Whether you are considering Wegovy, Mounjaro or another treatment, our experienced team can help you find the safest and most effective approach.

Reach out or complete an online consultation form today to discuss your options and begin your tailored weight loss plan. We are here to guide you through every step, from understanding the treatments to supporting you on your journey to better health and wellbeing.

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Written by Gavin Cheema, Superintendent Pharmacist. GPhC Number: 2214516.
With over eight years of experience in community, hospital, and online pharmacies, Gavin is a highly skilled Clinical Pharmacist and expert in UK pharmacy regulation. He has a deep understanding of medicines, compliance, and patient safety, ensuring onlinemeds operates to the highest standards while providing safe and accessible care.